We are engaged in the design and synthesis of orexin receptor agonists,
and also opioid research in WPI-IIIS, University of Tsukuba.

University of Tsukuba, International Institute for Integrative Sleep Medicine (WPI-IIIS)Nagase Laboratory (Medicinal Chemistry)

May. 16, 2016

Dr.Yamamoto and Mr.Koyama made a presentation at French- Japanese Symposium on Medicinal and Fine Chemistry (FJS 2016).

Dr.Yamamoto

Date ：May. 16, 2016

Title ：Synthesis of Novel, Potent and Highly Selective Orexin 1 Receptor Antagonists with a Morphinan Skeleton

Mr.Koyama

Date ：May. 16, 2016
Title ：Development of efficient synthesis of antitrichomonal BNTX derivatives and discovery of new rearrangement reaction

May. 13, 2016

Prof. Nagase gave a lecture at GPCR.

Date ：2016/5/13　13:05-13:40

Apr. 27, 2016

“難治性掻痒症治療薬ナルフラフィンの研究開発” was featured on SAR News 2016, No. 30, 2-7.

Apr. 26, 2016

YNT-185・2HCｌ was released from Wako Pure Chemical Industries, Ltd..

Apr. 26, 2016

”Design and Synthesis of Non-Peptide, Selective Orexin Receptor 2 Agonists” was featured on MEDCHEM NEWS Vol.26 (2) 90-96 (2016).

J. Med. Chem., 2015, 58 (20), pp 7931–7937

DOI: 10.1021/acs.jmedchem.5b00988

IIIS Building 4F, University of Tsukuba

1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575 TEL/FAX +81-29-853-6568

We are engaged in the design and synthesis of orexin receptor agonists, and also opioid research in WPI-IIIS, University of Tsukuba.