We are engaged in the design and synthesis of orexin receptor agonists,
and also opioid research in WPI-IIIS, University of Tsukuba.

2013/12

We completed to apply for a patent about our current researches.

We thank for all who may concerned.

 

We wish you a Happy New Year!

Dec. 2013

 

Ishikawa, K.; Tomatsu, M.; Nagase, H.; Fujii, H.

“Zinc-Acetic Acid Promoted Reductive Carbon-Nitrogen Bond Cleavage Reaction of α-Aminoketones”

Heterocycles 201488, 1051-1063. (web)

Dec. 12, 2013

Research Report of Dr. Saitoh was published in the research report of AMANO INSTITUTE  OF TECHNOLOGY.

 

Dec. 2013

Prof. Nagase was the guest speaker for the 79th Bio e-Cafe taking place on campus.

The event was held on December 11th and is open to everyone.

Detail is here(Japanese only).

Nov. 22, 2013

Our research was partially adopted as Adaptable and Seamless Technology transfer Program through target-driven R&D (A-STEP) by JST.

Nov. 20-22, 2013

Mr. Nakajima had a poster presentation on the 31st medicinal chemistry symposium (MCS2013).

2P-05: Design and synthesis of opioid delta selective propellane type quinoline derivatives

Nov. 18, 2013

Prof. Nagase gave a lecture on mini symposium 2013 of the society of synthetic organic chemistry, Kanto branch.

Detail is here (Japanese only).

Nov. 11, 2013

Dr. Yamamoto gave a lecture on IIIScience lounge.

The detail is here.

Nov. 5-6, 2013

Mr. Nakajima had a poster presentation on 39th symposium on progress in organic reactions and syntheses (Japanese only).

Oct. 31, 2013

1-s2.0-S0968089613009061-fx1

Nemoto, T.; Ida, Y.; Iihara, Y.; Nakajima, R.; Hirayama, S.; Iwai, T.; Fujii, H.; Nagase, H.

“The most effective influence of 17-(3-ethoxypropyl) substituent on the binding affinity and the agonistic activity in KNT-127 derivatives, δ opioid receptor agonists”
Bioorg. Med. Chem. 201321, 7628-7647. (web)

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We are engaged in the design and synthesis of orexin receptor agonists, and also opioid research in WPI-IIIS, University of Tsukuba.

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